14.5.

• 13.00 Arrival and Accommodation
• 14.30-14.45 Opening - Tomáš Obšil
• 14.45-15.15 Introductory lectures of PhD students (1 year students - 5 min – 5 slides/each) : 01 - Martin Orságh, 02 - Ipsita Padhee, 03 - Jun Xie, 04 - Daria Sudakova, 05 – Andrej Šmelko
• 15.15-16.15 Future plans – Assistant Professors (6-8 min) : 01 – Lucie Nová, 02 – Oleg Rud, 03 – Pavla Eliášová, 04 – Jan Přech, 05 – Michal Mazur, 06 – Ondřej Sedláček, 07 – Junji He
• 16.15-16.25 Presentation of NMR Laboratory (Z. Tošner)
• 16.30-18.00 Free afternoon – volleyball (P. Eliášová, M. Mazur)
• 18.30 Dinner at the fire (it depends on the weather)

15.5.

• 9.00-10.40 Lectures of PhD students (5 x 15 min + 5 min discussion): 01 - Manayath Panakkal, 02 - David Šorm, 03 - Zuzana Vosáhlová, 04 - Klára Kohoutová, 05 - Behlssen Hleli
• 10.40-11.00 Coffee break
• 11.00-12.20 Lectures of PhD students (4 x 15 min + 5 min discussion): 06 - Sebastian Pineda, 07 - Anastasia Kurbanova, 08 - Indranil Saha, 09 – Min Li
• 12.30-14.00 Lunch
• 14.00-15.20 Postdoc Lectures (4 x 15 min + 5 min discussion): Po01 - Subha Samantha, Po02 – Luis Carracosa, Po03 – Zhaobo Zhou, Po04 - Carlos Bornes
• 15.30-16.00 Coffee break
• 16.00-18.00 Pavla Hubálková (Charles University), Otakar Fojt (British Embassy Prague) Communication in Science
• 19.00 Dinner

16.5.

• 8.00 Breakfast and Departure

Electrolytes and interphases in Post Li batteries

We have a guest, Dr. Josef Bártl form the 1st Medical Faculty. His talk will be about The role of mass spectrometry in the diagnosis of inherited metabolic disorders.

Inherited metabolic disorders (IMDs) encompass a range of conditions displaying clinical symptoms caused by enzyme deficiencies, abnormal cell membrane function, or receptor irregularities stemming from genetic mutations. These variations lead to disruptions in biochemical metabolism, resulting in the accumulation of toxic metabolites or the depletion of essential compounds. IMDs manifest with a wide range of symptoms, affecting various organ systems at any age and are associated with a large heterogenous spectrum of biochemical markers. Hence, this poses challenge in early laboratory diagnostic and following management. Mass spectrometry (MS) represents a rapid analytical tool characterized by heigh sensitivity and specificity. It enables the simultaneous assessment of various IMDs including amino acid disorders, organic acidemias, and fatty acid oxidation disorders within a single experiment. The adoption of tandem mass spectrometry (MS/MS) facilitates the concurrent measurement of multiple metabolites, thus allowing the detection of multiple diseases from a single sample. In our biochemical laboratory we are focused on developing analytical methods for detecting IMDs employing various biological samples, like serum/plasma, urine, CSF, blood and dried blood spot (DBS). Based on over two decades of experience in LC/GC-MS/MS area we have developed comprehensive analytical algorithm for targeted metabolomics applied in newborn screening and selective screening of IMDs. It contributes to higher efficacy in diagnostic procedure and enhances patient outcomes and quality of their life.

We have a guest, Dr. Tomáš Etrych form the Institute of Macromolecular Chemistry, Czech Academy of Sciences. His talk will be about Hydrophilic and amphiphilic copolymers for therapy and diagnostics.

The conjugation of low-molecular-weight therapeutics with water-soluble or amphiphilic polymer carriers have several advantages, e.g. reduced drug toxicity, prolonged drug circulation in blood and higher accumulation of low-molecular-weight therapeutics in tumor or inflamed tissue, and enable highly effective tumor and anti-inflammatory therapy with minimized side effects. In ourgroup we study synthetic polymer carriers based on the methacrylamides as suitable drug delivery vectors. The accumulation of these polymer carriers in tumor or inflamed tissue is molecular-weight dependent. In addition, the size and shape of the polymer carriers is crucial for their biological behavior, therefore various structures were synthesized and will be presented. Importantly, such polymer vectors can be advantageously used also as diagnostics or theranostics. Amphiphilic conjugates with photosensitizers and hydrophilic conjugates with fluorescent near-infrared dyes will be shown and their effect in photodynamic therapy or navigated surgery will be mentioned. Last, but not least, the results of collaborative  research with companies will be presented during the lecture.

Mgr 1st/2nd year - Nováková, Pokorná, Mrzlíková, Hýbl, Hašpl

Presentations of the first year master students - Willimetz, Živný, Dědek, Šliková, Laštovičková

Paramagnetic NMR - the glimpse into the toolbox for material and catalyst characterisation

Presentations of the 1st year master students (Veselá, Krakl, Olšovská, Illés)

The 2nd year MSc. students will present their research topics:

• Kevin Kotalík
• Adam Brzezina
• Andrej Tekel
• Ondrej Kopilec
• Pavlína Šliková

The seminar will take place in person, in the hall CH3, Faculty of Science, Hlavova 8, Praha 2.

The 2nd year MSc. students will present their research topics:

• Daniel Berdár
• Petr Eminger
• Magdaléna Nejedlá
• Adam Hašpl
• Tímea Dérerová

The seminar will take place in person, in the hall CH3, Faculty of Science, Hlavova 8, Praha 2.

Filip Uhlík delivers his professorship lecture Chemistry by rolling dices.

Monte Carlo methods can be applied essentially to any problem. For most they would be quite poor, but there are some where they win and sometimes they are the only applicable methods we have. With costs of computing steadily and rapidly decreasing, their embarrassingly parallel nature is another advantage. In this lecture I would like to cover various aspects of the versatile Hamiltonian Monte Carlo method and to give several examples how it can be applied to studying problems of chemical interests.

The lecture will take place in person, in the hall CH3, Faculty of Science, Hlavova 8, Praha 2.